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Groundbreaking Clinical Trial for Squamous Cell Lung Cancer

A unique public-private collaboration among the National Cancer Institute (NCI), part of the National Institutes of Health, SWOG Cancer Research, Friends of Cancer Research (Friends), the Foundation for the National Institutes of Health (FNIH), five pharmaceutical companies (Amgen, Genentech, Pfizer, AstraZeneca, and AstraZeneca's global biologics R&D arm, MedImmune), Foundation Medicine and lung cancer advocacy groups, including LCA, today announced the initiation of the Lung Cancer Master Protocol (Lung-MAP) trial.   

Lung-MAP is a multi-drug, multi-arm, biomarker-driven clinical trial for patients with advanced squamous cell lung cancer. Squamous cell carcinoma represents about a quarter of all lung cancer diagnoses, but there are currently few treatment options beyond surgery for the disease. The trial will use genomic profiling to match patients to one of several different investigational treatments that are designed to target the genomic alterations found to be driving the growth of their cancer. This innovative approach to clinical testing should both improve access to promising drugs for patients and ease the significant recruitment and infrastructure burdens on researchers involved in traditional clinical trials.

Lung-MAP is poised to usher in one of the most dramatic advancements in cancer research that we have seen in years- and it will start first with our community – those diagnosed with squamous cell lung cancer.   

For more information on Lung-MAP, call our HelpLine: 1-800-298-2436.